How to cite item

Profiling HBV integrations in hepatocellular carcinoma

  
@article{HBSN1169,
	author = {Shaogui Wan and Jesse Civan and Simona Rossi and Hushan Yang},
	title = {Profiling HBV integrations in hepatocellular carcinoma},
	journal = {Hepatobiliary Surgery and Nutrition},
	volume = {2},
	number = {2},
	year = {2012},
	keywords = {},
	abstract = {Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide. In this context, chronic viral hepatitis B (HBV) infection represents the most common etiology of HCC. Notably, although other common causes of HCC including chronic viral hepatitis C and chronic alcoholic liver disease are mediated by progression through cirrhosis, the pathogenesis of HCC in HBV infection does not entirely depend on this mechanism. A major proposed pathway by which HCC may arise from chronic HBV infection is the integration of HBV DNA into the host genome, resulting in oncogene activation, tumor-suppressor gene inactivation, or other predisposition to chromosomal instability (1).},
	issn = {2304-389X},	url = {https://hbsn.amegroups.org/article/view/1169}
}