@article{HBSN22839,
author = {Cheng Zhou and Yuanfei Peng and Kaiqian Zhou and Lan Zhang and Xiangyu Zhang and Lei Yu and Jie Hu and Feiyu Chen and Shuangjian Qiu and Jian Zhou and Jia Fan and Zhenggang Ren and Zheng Wang},
title = {Surgical resection plus radiofrequency ablation for the treatment of multifocal hepatocellular carcinoma},
journal = {Hepatobiliary Surgery and Nutrition},
volume = {8},
number = {1},
year = {2018},
keywords = {},
abstract = {Background: To compare the efficacy and safety of surgical resection plus radiofrequency ablation (SR-RFA) with transarterial chemoembolization (TACE) in patients with multifocal hepatocellular carcinoma (HCC) beyond the Milan criteria.
Methods: From 2009 to 2015, a total of 469 consecutive patients with multifocal HCC beyond the Milan criteria (≤5 nodules) treated with SR-RFA (n=59) or TACE (n=410) were analyzed. Their overall survival (OS) rate was compared through propensity score matching (PSM) analysis at a ratio of 1:2, and 141 patients were identified (SR-RFA, n=47; TACE, n=94). Subgroup analysis was conducted according to factors associated with treatment options.
Results: Before PSM, the 1-, 2- and 3-year OS rates were 81.5%, 68.3% and 64.3% in the SR-RFA group and 58.7%, 35.5% and 24.4% in the TACE group, respectively (all P},
issn = {2304-389X}, url = {https://hbsn.amegroups.org/article/view/22839}
}