@article{HBSN2810,
author = {Camilla P. Stice and Xiang-Dong Wang},
title = {Carotenoids and alcoholic liver disease},
journal = {Hepatobiliary Surgery and Nutrition},
volume = {2},
number = {5},
year = {2013},
keywords = {},
abstract = {Chronic and excessive consumption of alcohol leads to the development of alcoholic liver disease (ALD). The depletion of vitamin A is a well-known consequence of alcohol consumption, and may be associated with the observed alcohol-induced hepatic injury. The provitamin A carotenoid β-carotene has been demonstrated to increase alcohol-induced hepatic injury when given in high doses, while low dose supplementation provides protection against hepatic injury. However, it is unknown if the hepatoprotective effects of low dose β-carotene are due to the protective actions of β-carotene itself or if the alterations are due to restored vitamin A levels. Future studies are needed to provide further insight into the specific mechanisms by which β-carotene exerts its protective effect. Further, supplementation studies utilizing high doses of β-carotene in the presence of alcohol must be done with caution.},
issn = {2304-389X}, url = {https://hbsn.amegroups.org/article/view/2810}
}