@article{HBSN32441,
author = {Riccardo Pravisani and Akihiko Soyama and Shinichiro Ono and Umberto Baccarani and Miriam Isola and Mitsuhisa Takatsuki and Masaaki Hidaka and Tomohiko Adachi and Takanobu Hara and Takashi Hamada and Florian Pecquenard and Andrea Risaliti and Susumu Eguchi},
title = {Is there any correlation between liver graft regeneration and recipient’s pretransplant skeletal muscle mass?—a study in extended left lobe graft living-donor liver transplantation},
journal = {Hepatobiliary Surgery and Nutrition},
volume = {9},
number = {2},
year = {2019},
keywords = {},
abstract = {Background: The end-stage liver disease causes a metabolic dysfunction whose most prominent clinical feature is the loss of skeletal muscle mass (SMM). In living-donor liver transplantation (LDLT), liver graft regeneration (GR) represents a crucial process to normalize the portal hypertension and to meet the metabolic demand of the recipient. Limited data are available on the correlation between pre-LDLT low SMM and GR.
Methods: Retrospective study on a cohort of 106 LDLT patients receiving an extended left liver lobe graft. The skeletal muscle index (SMI) at L3 level was used for muscle mass measurement, and the recommended cut-off values of the Japanese Society of Hepatology guidelines were used as criteria for defining low muscularity. GR was evaluated as rate of volume increase at 1 month post-LT [graft regeneration rate (GRR)].
Results: The median GRR at 1 month post-LT was 91% (IQR, 65–128%) and a significant correlation with graft volume-to-recipient standard liver volume ratio (GV/SLV) (rho −0.467, P},
issn = {2304-389X}, url = {https://hbsn.amegroups.org/article/view/32441}
}