@article{HBSN5289,
author = {Helmut K. Seitz and Sebastian Mueller and Claus Hellerbrand and Suthat Liangpunsakul},
title = {Effect of chronic alcohol consumption on the development and progression of non-alcoholic fatty liver disease (NAFLD)},
journal = {Hepatobiliary Surgery and Nutrition},
volume = {4},
number = {3},
year = {2014},
keywords = {},
abstract = {A number of epidemiologic studies show a protective effect of light to moderate daily alcohol consumption on the development of non-alcoholic fatty liver disease (NAFLD). Although these small amounts of ethanol may prevent fatty liver, they may also be a risk factor for other diseases such as breast and colon cancer. Those individuals who have underlying hepatic steatosis or non-alcoholic steatohepatitis (NASH) should not use ethanol chronically since the data available at present do not support a beneficial effect of alcohol in this situation. Especially overweight and obese individuals may be more susceptible towards alcohol even at moderate doses. Animal experiments show a negative effect of ethanol on liver histology in either dietary or genetic NASH models. In addition, patients with NASH reveal a significant increased risk for hepatocellular cancer (HCC) even with social alcohol consumption. Thus, subjects with underlying NASH should abstain from alcohol at any amounts.},
issn = {2304-389X}, url = {https://hbsn.amegroups.org/article/view/5289}
}