@article{HBSN6648,
author = {Durgatosh Pandey and Pankaj Kumar Garg and Ashish Jakhetiya and Jyoti Sharma and S. H. Chandrashekhara},
title = {Markedly elevated liver transaminases following pancreaticoduodenectomy: celiac artery thrombosis in disguise},
journal = {Hepatobiliary Surgery and Nutrition},
volume = {4},
number = {5},
year = {2015},
keywords = {},
abstract = {A 63-year-old lady underwent classical pancreaticoduodenectomy with regional lymphadenectomy for periampullary cancer. Preoperative contrast-enhanced computed tomography (CECT) of abdomen revealed dilated common bile duct which showed abrupt cut-off at ampulla. CECT also revealed replaced right hepatic artery arising from the left gastric artery (Panels A-C). During surgery, gastroduodenal artery was test-clamped to confirm pulsations in the hepatic artery before being ligated. On third postoperative day, she was found to have altered sensorium. Liver function tests showed bilirubin of 10.9 mg%; however, liver transaminases were markedly elevated (AST of 2,095 U/L and ALT of 1,243 U/L)—prothrombin time was also elevated [international normalized ratio (INR) =2.2]. Postoperative CECT of abdomen and pelvis revealed thrombosis of celiac artery trunk resulting in marked liver and spleen necrosis. Distal right hepatic artery was reformed by the collaterals; it explains relative sparing of right lobe of liver (Panels D-F).},
issn = {2304-389X}, url = {https://hbsn.amegroups.org/article/view/6648}
}