Original Article
Role of C11-FDG dual-tracer PET-CT scan in metastatic screening of hepatocellular carcinoma—a cost-effectiveness analysis
Dual-tracer PET-CT is cost-effective and useful for preoperative HCC staging in patients with AFP ≥400ng/ml or bilobar disease. Its routine use in preoperative workup for all HCC patients is not recommended because unilobar disease with AFP <400ng/ml has good negative predictive value.
Liver transplantation: would it be the best and last chance of cure for hepatocellular carcinoma with major venous invasion?
Although PVTT in HCC has been considered a sinister feature and hence a contraindication for LT for the sake of better liver graft utility, this study demonstrates that LT can confer much better oncological outcomes compared to hepatectomy in the context of HCC with PVTT.
A simple scoring system to estimate perioperative mortality following liver resection for primary liver malignancy—the Hepatectomy Risk Score (HeRS)
The Hepatectomy Risk Score (HeRS) incorporates the extent of resection and a MELD-Na score category to predict 30-day mortality after resection of primary liver malignancy. More complicated models offer better performance but at the expense of being more difficult to integrate into clinical practice.
The beneficial impacts of splanchnic vasoactive agents on hepatic functional recovery in massive hepatectomy porcine model
Excessive postoperative portal pressure, a major cause of post-hepatectomy liver failure and small-for-size syndrome after partial liver transplantation, is a difficult problem to be solved. Pharmacologic portal modulation with splanchnic vasoactive agents could optimize liver regeneration and attenuate liver injury after massive hepatectomy.
Review Article
Liver tissue microbiota in nonalcoholic liver disease: a change in the paradigm of host-bacterial interactions
We highlight the evidence on the role of non-intestinal microbiotas in liver diseases with emphasis on liver tissue bacterial DNA in the biology of NAFLD and NASH. Also, we provide evidence of metagenomic findings that can be leveraged to discover novel therapeutic targets.
French Editorial from the ACHBPT1
Editorial
Viewpoint
Letter to the Editor
Images in Clinical Medicine2
Disclosure:
1. The series “French Editorial from the ACHBPT” was commissioned by the editorial office, Hepatobiliary Surgery and Nutrition without any sponsorship or funding.
2. The series “Images in Clinical Medicine” was commissioned by the editorial office, Hepatobiliary Surgery and Nutrition without any sponsorship or funding.
