Vol 14, No 4 (August 01, 2025): Hepatobiliary Surgery and Nutrition

Original Article

The risk of hepatocellular carcinoma recurrence after liver transplantation increases with locoregional therapies in patients initially within Milan criteria
Jinsoo Rhu, Namkee Oh, Gyu-Seong Choi, Jongman Kim, Jae-Won Joh
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:539-551
.
The novel study design by including only initially within Milan hepatocellular carcinoma patients enabled clearer view of increasing risk of recurrence with the increasing number of locoregional therapies.
Biliary and respiratory complications after right hepatectomy for hepatocellular carcinoma following selective internal radiation therapy (SIRT): a retrospective case-control study
Bader Al Taweel, Gianluca Cassese, Azhar Meerun, Benjamin Rivière, Francis Navarro, Boris Guiu, Fabrizio Panaro
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:552-561
.
SIRT may increase the risk of biliary leakage and diaphragmatic dysfunction after right hepatectomy in cirrhotic patients with hepatocellular carcinoma. Surgeons must be aware of these potential complications while considering the downstaging benefits of this technique.
Hypothermic oxygenated machine perfusion does not increase the risk of infection after liver transplantation: a retrospective cohort study
Silvia Corcione, Damiano Patrono, Nour Shbaklo, Luca Mirabile, Maria Roberta Fortunato, Tommaso Lupia, Paola Maffezzoli, Antonio Curtoni, Alessandro Bondi, Cristina Costa, Renato Romagnoli, Francesco Giuseppe De Rosa
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:562-574
.
This study demonstrates that hypothermic oxygenated machine perfusion in liver transplantation does not increase the risk of infection within 10 days post-transplantation, yielding similar patient and graft outcomes compared to static cold storage and supporting the efficacy of HOPE in expanding the donor pool.
Evaluation of outcomes of robotic liver surgery using the IWATE criteria
Francesco Toti, Marco Di Pangrazio, Federico Pinto, Alessandro Martinino, Lily Zhang, Colton Johnson, Francesco Maria Bianco, Pier Cristoforo Giulianotti
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:575-586
.
This article emphasizes that the IWATE criteria correlate well with surgical outcomes, and by removing the learning curve, perioperative results can accurately reflect procedural complexity rather than surgeon skills. Implementing this classification system could facilitate a stepwise approach to robotic liver surgery, addressing adoption barriers.
Efficacy of hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma: survival outcomes and prognostic factors from a systematic review and meta-analysis
Di Zeng, Zhimeng Cheng, Jiong Lu, Geng Liu, Bei Li
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:587-607
.
Hepatic arterial infusion chemotherapy (HAIC) may offer improved overall and progression-free survival compared to transarterial chemoembolization (TACE) in advanced hepatocellular carcinoma. Evidence suggests HAIC may be particularly beneficial in patients with adverse prognostic factors, while maintaining a more favorable safety profile in selected populations.

Review Article

From critical care to organ preservation: the potential role of hemadsorption in transplantation—a narrative review
Chunbao Jiao, Keyue Sun, Kumaran Shamugarajah, Mingyi Zhang, Chase J. Wehrle, Rebecca Panconesi, Sangeeta Satish, Omer Karakaya, Robert L. Fairchild, Koji Hashimoto, Charles Miller, Silvia Perez-Protto, Andrea Schlegel
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:608-629
.
Hemadsorption devices, widely studied in sepsis and other conditions with cytokine storm, show promise for organ transplantation, particularly in liver disease. Ex-situ machine perfusion systems provide a valuable platform to investigate its effects on immune response and cellular metabolism, which remain incompletely understood.

Editorial Commentary

Quest for an accurate and reproducible prognostic biomarker of severe acute pancreatitis: have we finally found it?
Peter J. Lee, Fred S. Gorelick, Georgios I. Papachristou
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:639-642
.
Updates on the impact of the new liver allocation policy on national liver transplants
Stephanie Y. Ohara, Michelle C. Nguyen, Amit K. Mathur, Peter E. Frasco, Bashar Aqel, Blanca C. Lizaola-Mayo, Caroline C. Jadlowiec
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:643-646
.
De-escalating local therapies without compromising outcomes: lessons from the COLLISION trial
Jessica Albuquerque, Noreen S. Siddiqi, Van K. Morris, Hop Tran Cao, Iwan Paolucci, Bruno C. Odisio
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:647-650
.
Empagliflozin for non-diabetic metabolic dysfunction-associated steatotic liver disease: a promising therapeutic agent in transition
Mohamed El-Kassas, Hongqun Liu, Samuel S. Lee
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:651-654
.
Neuroendocrine liver metastasis
Sonal Walia, Alexandra M. Roch, Eugene P. Ceppa
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:655-657
.
Listening to the spleen: a 100 Hz pulse toward a non-invasive way in assessing portal hypertension
Jeong-Ju Yoo, Young Seok Kim, Sang Gyune Kim
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:658-661
.
Advancing surgical techniques: a first application of remote robotic pancreaticoduodenectomy for resectable malignant tumor
Wen-Bo Zou, Zhao-Ping Wu, Wei-Li Chen, Ning-Bo Fang, Jian Yang, Guo-Dong Zhao
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:662-664
.
Navigating abdominal surgery in extrahepatic portal vein obstruction: new insights and remaining issues
Tetsuya Shimizu, Hiroshi Yoshida, Yoichi Kawano, Akira Matsushita, Masato Yoshioka, Junji Ueda
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:665-668
.
Can portable artificial livers become an alternative to liver transplantation in the future?
Liwei Du, Hongyuan Yi, Youkang Chen, Haifeng Xu
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:669-672
.
Balancing efficacy and tolerability in metastatic pancreatic cancer: lessons from the ALPACA trial
Tadahisa Inoue, Akihisa Kato, Michihiro Yoshida, Tomoya Kitada, Rena Kitano, Itaru Naitoh
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:673-675
.
Beyond chemotherapy in biliary tract cancer: a closer look at the updated long-term follow-up data of the TOPAZ-1 trial
Alexander Olkus, Michael T. Dill
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:676-679
.
How to improve the care of decompensated cirrhosis: the intervention model for chronic disease management
Beom Kyung Kim
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:680-682
.
Auxiliary liver transplantation using otherwise-discarded liver allograft combined with associating liver partition and portal vein ligation for staged hepatectomy for unresectable colorectal liver metastases
Zheng Wang, Xiaowu Huang, Yinghong Shi, Xiaoying Wang, Zhenbin Ding, Yongsheng Xiao, Yifeng He, Ting Wang, Jian Sun, Kang Song, Zaozhuo Shen, Lei Yu, Kai Zhu, Changhong Miao, Yuan Ji, Liuxiao Yang, Yingyong Hou, Qiang Gao, Jia Fan, Jian Zhou
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:683-688
.
The value of tranexamic acid in liver resection should not be exaggerated or ignored
Penglei Ge, Yang Wu
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:689-691
.
Construction and application of multicellular tumor microenvironment models based on three-dimensional bioprinting technology
Bo Zhou, Minghao Sun, Mian Yang, Wei Cui, Huayu Yang
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:692-696
.

Editorial

Running towards liver transplantation
Alberto Ferrarese, Andrea Gasperetti, Andrea Ermolao, Giacomo Germani, Patrizia Burra
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:697-699
.
Navigating the complexity of colorectal liver metastasis: molecular profiling and tumor sidedness
Sung Jun Jo, Jongman Kim
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:700-702
.
New perspectives in biology-driven treatment of cholangiocarcinoma: from oncological resectability to genetic breakthroughs and AI-powered imaging
Luca Viganò, Luca Risi, Angela Ammirabile
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:703-708
.
Developing a new source for organ transplantation
Shunda Du, Yilei Mao
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:709-711
.
Call a spade a spade
Elke Roeb
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:712-715
.

Letter to the Editor

Primary Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma concurrent with lymphoepithelioma-like intrahepatic cholangiocarcinoma and cavernous hemangioma in liver
Congwei Jia, Jinyi Meng, Can Yin, Xuemei Sun, Yan You, Lei Zhang, Xiaoyan Chang
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:716-719
.
An intriguing case of macrolides-induced pancreatic injury mimicking pancreatic carcinoma
Kun He, Zihan Yang, Ziqi Guo, Hongwei Wang, Jia Xu, Long Zou, Yunlu Feng, Wen Shi, Dong Wu, Aiming Yang
HepatoBiliary Surgery and Nutrition  
2025;
14
(4)
:720-723
.