Vol 15, No 2 (April 01, 2026): HepatoBiliary Surgery and Nutrition

Original Article

Liver transplantation for hepatocellular carcinoma arising in non-cirrhotic liver: a national-wide retrospective cohort study with propensity score matching analysis in China
Qiang Wei, Nan Xu, Yunguo Lei, Yisu Song, Zhisheng Zhou, Shengjun Xu, Xuanyu Zhang, Shusen Zheng, Jun Chen, Xiao Xu
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:33
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There is limited research focusing on recipients without cirrhosis, especially in East Asia. This study demonstrates that liver transplantation for non-cirrhotic hepatocellular carcinoma has a poor prognosis compared with cirrhotic hepatocellular carcinoma.
Association of a novel glycemic control index, time in range, with infectious complications after pancreatectomy
Yuichiro Kohara, Satoshi Yasuda, Minako Nagai, Kyohei Matsumoto, Kota Nakamura, Yasuko Matsuo, Taichi Terai, Shunsuke Doi, Takeshi Sakata, Atsushi Shimizu, Hideki Motobayashi, Manabu Kawai, Masayuki Sho
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:34
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The study provides useful information on the relationship between time-in-range and organ/space surgical site infection after pancreatectomy. The findings indicate that a time-in-range <75% during the first week after pancreatectomy is a significant risk factor for organ/space surgical site infection.
EREG-secreting THBS1+ tissue monocytes are recruited by C5a to promote rapid liver regeneration in patients and mice during the ALPPS procedure
Feiyu Chen, Jiayan Yan, Zhifeng Jiang, Jianwen Cheng, Na Yao, Ao Huang, Shiyu Zhang, Yang Xu, Haixiang Sun, Zheng Wang, Zhaoyou Tang, Xiangdong Wang, Jia Fan, Xinrong Yang, Jian Zhou
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:35
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The first report of human liver local immune microenvironment changes during rapid regeneration induced by ALPPS. THBS1+ tissue monocytes recruit by C5a are significantly enriched in FLR resulting a shift from a macrophage-enriched to monocyte-enriched local immune environment, promoting hepatocyte proliferation via EREG- EGFR interactions.
Impact of adjuvant therapy on survival outcomes in resected gallbladder cancer: a systematic review and meta-analysis
Di Zeng, Yaoqun Wang, Ningyuan Wen, Nansheng Cheng, Bei Li
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:36
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This meta-analysis assesses the impact of adjuvant therapies (chemotherapy, radiotherapy, and chemoradiotherapy) on survival outcomes in resectable gallbladder cancer. The results suggest that chemoradiotherapy is associated with improved survival, especially in patients with high-risk features, highlighting the need for personalized treatment strategies.
Phase II trial of hepatic arterial infusion chemotherapy plus bevacizumab and toripalimab for advanced biliary tract cancers: efficacy, safety, and exploratory analysis
Kanglian Zheng, Shijie Fu, Xu Zhu, Guang Cao, Liang Xu, Peng Liu, Song Gao, Haifeng Xu, Jianhai Guo, Hui Chen, Wei Liu, Da Xu, Lijun Wang, Xiaoluan Yan, Quan Bao, Jianhui Wu, Kun Wang, Jun Zhou, Chunyi Hao, Baocai Xing, Lin Shen, Renjie Yang, Xiaodong Wang
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:37
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HAIC combined with bevacizumab and toripalimab yielded encouraging outcomes as a first-line treatment for advanced BTCs in terms of ORR, PFS, OS, and an acceptable safety profile. Therefore, the triple combination therapy may be an improved first-line treatment for advanced BTC.
Does a patient who needs portal vein embolization (PVE) to proceed to major hepatectomy (MH) have the same hepatic functional reserve than a patient with no preoperative PVE?
Stéphanie Truant, Clio Baillet, Mehdi El Amrani, Katia Lecolle, Olivier Ernst, Sébastien Dharancy, Anthony Turpin, Damien Huglo, François-René Pruvot
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:38
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Some patients apparently-fit for surgery after PVE are going to hepatic resection with lower hepatic functional reserve and show altered functional regenerative capacities compared with patients without PVE. Special attention should be paid to such patients in the perioperative period.
Factors associated with textbook outcome after robotic-assisted pancreatoduodenectomy: a single surgeon’s retrospective cohort
Ai-Qing Fu, Xi-Tai Huang, Jian-Peng Cai, Chen-Song Huang, Xin Zhang, Qiong-Cong Xu, Wei Chen, Liu-Hua Chen, Xiao-Yu Yin
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:39
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In a single-surgeon cohort of RPD patients, TO was achieved in 57.0% of all patients and in 63.2% after surgeon’s learning curve. Surgeon’s learning curve, ASA score, concomitant diabetes, and dilated pancreatic duct (>3mm) were independently associated with TO.

Editorial Commentary

First randomized controlled trial comparing stereotactic body radiotherapy and radiofrequency ablation for hepatocellular carcinoma: lessons and key considerations for interpretation of results
Masayuki Ueno, Satoshi Itasaka, Motowo Mizuno
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:40
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Perioperative antibiotic prophylaxis in pancreatoduodenectomy: toward a new standard, but questions remain
Zachary A. Whitham, Adam C. Yopp
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:41
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Phenotypic personalized tacrolimus dosing: a step toward precision immunosuppression in liver transplantation
Christopher Hartley, Yan Shu, Wikrom Karnsakul
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:42
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Should nasogastric enteral feeding become a standard escalation to reverse malnutrition in liver transplant candidates?
Alexandra Nassar, Claire Francoz, Christian Hobeika
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:43
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The role of resection margin status on recurrence and selection of patients for adjuvant radiotherapy in distal cholangiocarcinoma
Mario De Bellis, Edoardo Poletto, Andrea Ruzzenente
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:44
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Hypovolemic phlebotomy and low central venous pressure: a paradigm shift in liver surgery?
Daniel Eyraud, André Cordeiro
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:45
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Balancing safety and outcomes in minimally invasive liver resection: insights from the PRESSURE trial
Nicholas Ken Jin Ang, Kah Ming Eddy Saw, Ye Xin Koh, Hwee Leong Tan, Darren Weiquan Chua
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:46
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Dapagliflozin for metabolic dysfunction-associated steatohepatitis with fibrosis: a promising therapeutic agent in biopsy-diagnosed patients
Soo Kyoung Kim, Hyeong Seok An, Gu Seob Roh
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:47
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The ESSENCE of hope: what semaglutide’s Food and Drug Administration approval means for metabolic dysfunction-associated steatohepatitis
Mariam Alamgir, Aalam Sohal, Kris V. Kowdley
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:48
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Revisiting the two-stage hepatectomy and hepatic arterial infusion chemotherapy for colorectal liver metastases: insights and long-term outcomes from a large cohort
Tom Vandaele, Mathieu D’Hondt
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:49
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Fabricating transplantable, vascularized, and cholangiogenic bioartificial livers via three-dimensional bioprinting: a promising therapeutic strategy for liver failure
Xiyue Liu, Huayu Yang
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:50
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How does obesity develop—and are specific foods to blame?
Faidon Magkos, Ciarán G. Forde
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:51
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Metabolic syndrome and cholangiocarcinoma: large numbers, small risks, but big implications
Usman Saeed, Sheraz Yaqub
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:52
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Evolution of two-stage hepatectomy: 25 years of modifications and lessons learned
Zenichi Morise
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:53
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Engineering the tumor microenvironment via 3D multicellular bioprinting for personalized immunotherapy assessment and resistance deciphering
Feihu Xie, Meiheban Bazhabayi, Yun Zheng
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:54
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Treat-to-target in pancreatic exocrine insufficiency: moving from symptom control to nutrition outcomes
Yamin Lai, Dong Wu
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:55
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Editorial

Challenges and innovations in adjuvant therapy for gallbladder cancer: a meta-analytic perspective
Daniel Neureiter, Matthias Ocker
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:56
.

Letter to the Editor

A rare case of giant paraganglioma in the first porta hepatis area associated with neurofibromatosis type 1
Xuming Zhang, Junqing Xie, Xianhui Lin, Linjing Huang, Xihao Zhong, Rongqi Chen, Leyan Di, Haibin Liu, Bin Zhou, Binglong Bai
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:57
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Pancreatobiliary maljunction accompanied by synchronous carcinomas
Jian Xu, Lixin Zhang, Guo Wu, Jing-Dong Li
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:58
.
Hybrid hepatic artery debranching for pancreatic cancer with celiac axis occlusion
Artur Rebelo, Johannes Klose, Jumber Partsakhashvili, Ulrich Ronellenfitsch, Jörg Ukkat, Jörg Kleeff
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:59
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Advancing the enhanced recovery after surgery paradigm in liver transplantation: evidence-based strategies for a comprehensive care continuum
Dipesh Kumar Yadav, Yisheng Zhang, Yiren Hu
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:60
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Robotic-assisted hepatopancreatoduodenectomy for intraductal papillary neoplasm of the bile duct: future approach for minimally invasive biliary surgery
Zhujing Lan, Tiansheng Lan, Weitao Chen, Keyu Huang, Jianyong Zhang, Weimin Mao, Bingcheng Meng, Jilong Wang, Ziqin Zhong, Tingting Lu, Rui Song, Banghao Xu, Hai Zhu, Zhang Wen
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:61
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Remote robot-assisted pancreatoduodenectomy for one patient with pancreatic ductal adenocarcinoma
Chen-Song Huang, Yuan-Yuan Chen, Xi-Tai Huang, Bin Liang, Wei-Tao Chen, Xiao-Yu Yin
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:62
.

Images in Clinical Medicine

Pancreatic adenosquamous carcinoma mimicking autoimmune pancreatitis
Wenfeng Xi, Zheng Wang, Wen Shi, Yunlu Feng, Aiming Yang
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:63
.

Erratum

Erratum: De-escalating local therapies without compromising outcomes: lessons from the COLLISION trial
Editorial Office
HepatoBiliary Surgery and Nutrition  
2026;
15
(2)
:64
.