Vol 15, No 3 (June 01, 2026): HepatoBiliary Surgery and Nutrition

The Story Behind the Cover Picture

D’Agoty’s early anatomical painting of the liver
Thomas M. van Gulik
HepatoBiliary Surgery and Nutrition  
2026;
15
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:65
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Original Article

Impact of metabolic dysfunction-associated steatotic liver disease on long-term prognosis in hepatocellular carcinoma patients undergoing hepatectomy
Qingyan Kong, Jiahui Yang, Diao Kong, Huanrui Hu, Bei Li, Wei Peng, Zheyu Chen
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:66
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This study reveals that metabolic dysfunction-associated steatotic liver disease (MASLD) is a significant risk factor for poor recurrence-free survival (RFS) and overall survival (OS) in hepatocellular carcinoma (HCC) patients undergoing hepatectomy, emphasizing the importance of preoperative MASLD diagnosis for prognosis guidance.
Enhanced long-term outcomes with laparoscopic bariatric surgery in patients with severe obesity and metabolic dysfunction-associated steatotic liver disease: a retrospective cohort study
Xinrong Zhang, Nicholas Rouillard, Xianhua Mao, Rongtao Lai, Ramsey Cheung, Kazunari Sasaki, Mindie H. Nguyen
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:67
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In this population-based study, laparoscopic surgery is associated with lower risk of liver and non-liver adverse outcomes, as well as lower healthcare utilization and pharmacy costs in patients with metabolic dysfunction-associated steatotic liver disease and severe obesity as compared to open surgery.
Prediction of postoperative early recurrence and response to adjuvant transcatheter arterial chemoembolization in hepatocellular carcinoma with microvascular invasion after hepatectomy: a multicenter study
Tian-Chen Zhang, Zhen-Qi Li, Wei-Li Jia, Yu Cao, Ming-Gen Hu, Kang Wang, Shuai Xu, Tao Jiang, Chao Lin, Xiong Chen, Guang Tan, Nian-Xin Xia, Wen-Chao Zhao, Mao-Lin Yan, Yun-Fei Xu, Xiao-Dong Tan, Fan Zhang, Xiao Wang, Yu-Fu Tang, Qing-Qiang Ni, Yi-Lin Hu, Shu-Qun Cheng, Xiu-Ping Zhang, Rong Liu
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:68
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A new calculator, the DCDAM score, utilizes diameter, cirrhosis, differentiation, AFP, and MVI grade to accurately predict early recurrence of HCC with MVI. Patients in the high-risk group (DCDAM score > 169) experience poor RFS and OS and respond well to postoperative adjuvant TACE.
Does neoadjuvant therapy reduce pancreatic fistula after pancreatoduodenectomy and distal pancreatectomy?—a systematic review and meta-analysis
Sandro Hügli, Victor Lopez-Lopez, Sarvar Abdurakhmonov, Jan Philipp Jonas, Elena Rangelova, Luana Genova, Giuseppe Malleo, Ryan K. Schmocker, Lea Timmermann, Thomas Malinka, Scott Helton, Ralph Fritsch, Fabian Kalt, Carol Ann Trachsel, Fabian Rössler, John Bryant, Russel Palm, Sarah E. Hoffe, Cristiano Guidetti, Fabrizio Di Benedetto, Daniel Pietrasz, Sameer H. Patel, Gregory C. Wilson, Syed A. Ahmad, Jin He, Changhoon Yoo, Julien Taieb, Henrik Petrowsky, Juan Lujan, Ricardo Robles-Campos, Ernesto Sparrelid, Jose Oberholzer, Dilmurodjon Eshmuminov
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:69
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This systematic review and meta-analysis found that neoadjuvant therapy significantly reduces the risk of postoperative pancreatic fistula (POPF) after pancreatoduodenectomy, likely due to induced pancreatic fibrosis. It suggests potential for improved surgical outcomes but emphasizes the need for individualized treatment based on predicted tumor response.

Review Article

A systematic review of methodology in nutritional trials in patients undergoing pancreatoduodenectomy
James M. Halle-Smith, Keshav Krishnan, Jasmin Kirupananthan, Kayaththery Varathan, Richard Laing, Mary E. Phillips, Keith J. Roberts, Andrew M. Smith, Samir Pathak
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:70
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There is evidence of widespread variation in the methodology amongst published trials of nutritional interventions in patients undergoing pancreatoduodenectomy. This makes comparing the effect of these different nutritional interventions on postoperative outcomes difficult and has implications for design of future nutritional trials in this area.
Precision transarterial chemoembolization in hepatocellular carcinoma: patient selection, standardized techniques, and quantitative evaluation
Bin-Yan Zhong, Zhongzhi Jia, Ho-Young Song, Wen Zhang, Li Chen, Dongdong Xia, Kelvin Hong, Jon C. Davidson, Justin J. Guan, Jim Zhong, Alex Tang, Zhenwei Peng, Cai-Fang Ni, Zhi-Ping Yan, Gao-Jun Teng
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:71
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With the aim to enhance quality control and standardize TACE procedures, the concept of "precision TACE" is introduced by ISMIO, emphasizing standardized angiography, superselective catheterization and embolization, appropriate selection of embolic agents, determination of optimal embolization endpoints, and evaluation for efficacy immediately post-TACE.

Expert Consensus

Chinese expert consensus on conversion and perioperative therapy of primary liver cancer (2024 edition)
Zheng Wang, Huichuan Sun, Jian Zhou, Qing Xie, Xinyu Bi, Xiufeng Liu, Rong Liu, Ming Zhao, Xueli Bai, Yuan Ji, Li Xu, Weidong Jia, Shaochong Zeng, Gong Li, Wei Zhang, Shunli Shen, Shengxiang Rao, Guoming Shi, Lan Zhang, Xiaodong Zhu, Zhifeng Wu, Jiabei Wang, Haowen Tang, Dousheng Bai, Yajin Chen, Yongjun Chen, Chaoliu Dai, Fangming Gu, Jinhe Guo, Rongping Guo, Wenzhi Guo, Feng Han, Guohong Han, Chunyi Hao, Tao Huang, Xiaolun Huang, Yangqing Huang, Zhiyong Huang, Shunchang Jiao, Deyu Li, Tao Li, Xiangcheng Li, Guangming Li, Ping Liang, Xiao Liang, Jinguan Lin, Fubao Liu, Jiwei Liu, Jingfeng Liu, Zheng Lu, Weifu Lv, Yilei Mao, Zhiqiang Meng, Chuang Peng, Li Peng, Tao Peng, Ming Shi, Yinghong Shi, Tianqiang Song, Guang Tan, Yunqiang Tang, Kaishan Tao, Chidan Wan, Guangyi Wang, Kui Wang, Lu Wang, Maoqiang Wang, Shunxiang Wang, Wentao Wang, Tianfu Wen, Bangde Xiang, Baocai Xing, Jianming Xu, Jun Xu, Sheng Yan, Dinghua Yang, Jiayin Yang, Guowen Yin, Zhengping Yu, Yongyi Zeng, Jialin Zhang, Shuijun Zhang, Ti Zhang, Yamin Zhang, Yu Zhang, Yubao Zhang, Zhiwei Zhang, Aibin Zhang, Haitao Zhao, Hong Zhao, Ledu Zhou, Weiping Zhou, Zhenyu Zhu, Shukui Qin, Feng Shen, Xiujun Cai, Jianqiang Cai, Minshan Chen, Qiang Li, Lianxin Liu, Weilin Wang, Tingbo Liang, Bixiang Zhang, Shichun Lu, Shuqun Cheng, Zhenggang Ren, Hong Wu, Ming Kuang, Gaojun Teng, Kefeng Dou, Jiahong Dong, Xiaoping Chen, Xuehao Wang, Shusen Zheng, Jia Fan; Alliance of Liver Cancer Conversion Therapy, Liver Cancer Committee, China Anti-Cancer Association
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:72
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This updated 2024 Chinese expert consensus details conversion and perioperative strategies for hepatocellular carcinoma (HCC). It refines definitions and integrates new systemic and locoregional therapies with surgery to downstage tumors for resection. A multidisciplinary collaboration approach is emphasized to improve long-term survival for HCC patients.

French Editorial Commentary from the ACHBPT

Towards omission of drainage in distal pancreatectomy—the PANDRA II study: another brick in the wall!
Emmanuel Devant, Mircea Chirica
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:73
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Editorial Commentary

Liver dysfunction associated with severe acute pancreatitis: molecular mechanisms and clinical insights
Wumeng Jin, Shuifang Jin
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:74
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Refining the boundaries of resectability for colorectal cancer liver metastases with extrahepatic disease—surgical lessons from a nationwide analysis
Alexander S. Thomas, Samer T. Tohme, David A. Geller
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:75
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Benchmarking performance in robotic liver resection: are we measuring what matters?
Francesca Tozzi, Filip Gryspeerdt, Hasan Eker, Niki Rashidian
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:76
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Global benchmarks for robotic liver resection: Eastern excellence calls for reevaluation in the West
Nagoud Schukfeh, Stefanie Langreen
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:77
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Revisiting treatment paradigms for colorectal liver metastases: liver transplant or associating liver partition and portal vein ligation for staged hepatectomy?
Antonia Alina Geisler, Robert Sucher, Andri Lederer
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:78
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Pushing to resect colorectal liver metastases: rethinking surgical strategy in colorectal liver metastases with extrahepatic spread
Tor Magnus Smedman, Pål-Dag Line, Svein Dueland
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:79
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Adjuvant therapy after R0 resection for primary hepatic sarcomatoid carcinoma
Takehiro Noji, Toshimichi Asano, Satoshi Hirano
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:80
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Pushing the boundaries of surgical resectability in colorectal liver metastases: the advancing role of two-stage hepatectomy
Sebastian Knitter, Felix Krenzien, Nathanael Raschzok, Johann Pratschke, Wenzel Schöning
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:81
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Transplantation for unresectable perihilar cholangiocarcinoma beyond the Mayo protocol: a challenge for SURE
Hendrien Kuipers, Rory L. Smoot, Frederik J. H. Hoogwater
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:82
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Outcomes after surgery for locally advanced pancreatic cancer compared to borderline and upfront resectable pancreatic cancer
Kjetil Soreide, Nigel B. Jamieson
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:83
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Advancing risk stratification in intermediate-stage hepatocellular carcinoma undergoing transarterial chemoembolization: the promise of the NTAA model
Zuzanna Kobus, Hooman Yarmohammadi
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:84
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Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) vs. liver transplantation for borderline-resectable colorectal liver metastases: evidence not yet definitive
Georgios Antonios Margonis, Felix Balzer
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:85
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Hepatocellular carcinoma surveillance—is it time to update clinical practice?
Jessica Yang, Jacob George
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:86
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Survival after resection of pancreatic cancer is similar with neoadjuvant gemcitabine-nab-paclitaxel or mFOLFIRINOX but one size will not fit all in the future
Sophia Hernandez, Ajay V. Maker
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:87
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Moving the needle on donation after circulatory death procedures
Anji Wall, Giuliano Testa
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:88
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Rethinking nutritional risk in cancer: muscle quality, myosteatosis, and prognosis
Shangze Jiang, Haifeng Xu
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:89
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Refining prognostication in intermediate-stage hepatocellular carcinoma after transarterial chemoembolization: promise and limitations of the proposed NTAA model
Philipp Schindler, Max Masthoff
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:90
.
Sex disparity in liver cancer recurrence—from bench to bedside
Takeshi Yamada, Kay Uehara, Hiroshi Yoshida
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:91
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The evolution of liver graft preservation strategies in liver transplantation
Wei Gao, Jiu-Lin Song, Shan Huang, Zhong-Yuan Cai, Zhen-Yu Duan, Xi Xu, Chen Jin, Tao Lv, Gang Xu, Jia-Yin Yang
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:92
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Letter to the Editor

Immune-mediated tumor regression and subsequent escape driven by antigen loss and major histocompatibility complex (MHC) class I downregulation following GPC3 DNA vaccination in hepatocellular carcinoma
Hang Li, Xudong Wang, Zhentao Yan, Siyuan Weng, Wendi Kang, Junqing Xi, Zhengqiang Yang
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:93
.
A novel anastomotic technique reducing biliary complications in small-duct reconstruction during adult living donor liver transplantation
Jun Wu, Gang Xu, Youlong Wu, Jingsheng Yuan, Yongjie Zhou, Jian Yang, Jiulin Song, Lingxiang Kong, Xi Xu, Tao Lv, Jiayin Yang
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:94
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Single-port robotic pancreaticoduodenectomy with the SHURUI snake-arm system: first clinical application
Jianjun Leng, Jian Feng, Chenglin Piao, Qiang Li, Xin Lan, Zhenduo Si, Chao Zhang, Fengduo An
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:95
.

Images in Clinical Medicine

Wandering spleen
Zeyu Zhang, Lei Zhang, Xiao Liu, Haifeng Xu
HepatoBiliary Surgery and Nutrition  
2026;
15
(3)
:96
.