Giant hepatocellular carcinoma
A 40-year-old female presented with progressive abdominal enlargement for 6 months (Panel A), along with severe abdominal distension and amenorrhea. She had not gone to hospital because she assumed herself to be pregnant, until the belly grew out of control. A giant lesion in abdomen was detected by computed tomography (Panel B). The patient was infected with hepatitis B virus, but the liver function and α-fetoprotein were normal. Additionally, no distant metastasis was found preoperatively. The pre-operative diagnosis of the tumor origin was unclear. Exploratory laparotomy was performed and an exophytic tumor originating from the liver was exposed. The patient underwent major hepatectomy (Panel C). Postoperative pathology is moderately differentiated hepatocellular carcinoma (hematoxylin and eosin stain, ×20) (Panel D). Transarterial chemoembolization and sorafenib was administrated postoperatively. At a recent 3-month follow-up, no recurrence occurred.
Acknowledgments
The authors thank to Dr. Shunda Du for providing technical help to this research.
Funding: This study was funded by CAMS Innovation Fund for Medical Sciences (CIFMS) (No. 2016-I2M-1-001), Tsinghua University-Peking Union Medical College Hospital Cooperation Project (PTQH201904552) and Peking Union Medical College Graduate Student Innovation Fund (No. 2019-1002-45).
Footnote
Provenance and Peer Review: This article was commissioned by the editorial office, Hepatobiliary Surgery and Nutrition. The article did not undergo external peer review.
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://hbsn.amegroups.org/article/view/10.21037/hbsn-20-727/coif). YM serves as an unpaid editorial board member of Hepatobiliary Surgery and Nutrition. The other author has no conflicts of interest to declare.
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