Vol 11, No 1 (February 01, 2022): Hepatobiliary Surgery and Nutrition

Original Article

Comparison of alternative arterial anastomosis site during liver transplantation when the recipient’s hepatic artery is unusable
Jean Marie Beaurepaire, Francesco Orlando, Giovanni Battista Levi Sandri, Caroline Jezequel, Edouard Bardou-Jacquet, Christophe Camus, Mohamed Lakehal, Veronique Desfourneaux, Aude Merdrignac, Elodie Gaignard, Alexandre Thobie, Damien Bergeat, Bernard Meunier, Michel Rayar
During liver transplantation, when the recipient’s hepatic artery is unusable, an arterial anastomosis performed on the recipient’s splenic or coeliac trunk is associated with better intraoperative and postoperative outcomes.
Gd-EOB-DTPA-enhanced MRI radiomic features for predicting histological grade of hepatocellular carcinoma
Yingfan Mao, Jincheng Wang, Yong Zhu, Jun Chen, Liang Mao, Weiwei Kong, Yudong Qiu, Xiaoyan Wu, Yue Guan, Jian He
Radiomic features based on Gd-EOB-DTPA-enhanced MRI performed well in predicting histological grade of hepatocellular carcinoma, with AUCs of 0.777 to 0.944. Compared with traditional logistic regression model, Artificial neural network showed potential advantages in distinguishing between high-grade and low-grade HCCs.
Preservation of aberrant right hepatic arteries does not affect safety and oncological radicality of pancreaticoduodenectomy—own results and a systematic review of the literature
Cedrik Pyras, Carsten Lukas, Monika Janot-Matuschek, Torsten Herzog, Andrea Tannapfel, Waldemar Uhl, Orlin Belyaev
Associating liver partition and portal vein ligation for staged hepatectomy versus sequential transarterial chemoembolization and portal vein embolization in staged hepatectomy for HBV-related hepatocellular carcinoma: a randomized comparative study
Peng-Peng Li, Gang Huang, Ning-Yang Jia, Ze-Ya Pan, Hui Liu, Yun Yang, Cheng-Jian He, Wan Yee Lau, Ye-Fa Yang, Wei-Ping Zhou
This article provides relatively high-level evidence about the merits and demerits of ALPPS compared with PVE, especially in patients with HBV related HCC, pointing out the higher resection rates and longer OS of ALPPS at the cost of a higher postoperative morbidity rate.
Development and internal validation of the Comprehensive ALPPS Preoperative Risk Assessment (CAPRA) score: is the patient suitable for Associating Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS)?
Ivan Capobianco, Karl J. Oldhafer, Mohammed-Hossein Fard-Aghaie, Ricardo Robles-Campos, Roberto Brusadin, Henrik Petrowsky, Michael Linecker, Arianeb Mehrabi, Katrin Hoffmann, Jun Li, Asmus Heumann, Roberto Hernandez-Alejandro, Mauro Enrique Tun-Abraham, Elio Jovine, Matteo Serenari, Bergthor Bjornsson, Per Sandström, Ruslan Alikhanov, Mikhail Efanov, Paolo Muiesan, Andrea Schlegel, Thomas M. van Gulik, Pim B. Olthof, Gregor Alexander Stavrou, Lina Maria Serna-Higuita, Alfred Königsrainer, Silvio Nadalin
The CAPRA Score, based on patient condition and type of procedure, has excellent preoperative prediction of 90-day mortality risk in ALPPS. It therefore provides additional support in patient selection and procedure planning, in combination with already validated scores, volumetry and liver function assessments.
Intraoperative reperfusion assessment of human pancreas allografts using hyperspectral imaging (HSI)
Robert Sucher, Uwe Scheuermann, Sebastian Rademacher, Andri Lederer, Elisabeth Sucher, Hans-Michael Hau, Gerald Brandacher, Stefan Schneeberger, Ines Gockel, Daniel Seehofer
This article describes the first application of hyperspectral imaging in human pancreas allografts. Our novel non-invasive technique is capable to deliver real time visual and quantitative information about the tissue oxygenation, perfusion as well as hemoglobin and water concentration of the organ, subject to investigation.
Liver resection versus liver transplantation for hepatocellular carcinoma within Milan criteria: a meta-analysis of 18,421 patients
Jin Hean Koh, Darren Jun Hao Tan, Yuki Ong, Wen Hui Lim, Cheng Han Ng, Phoebe Wen Lin Tay, Jie Ning Yong, Mark D. Muthiah, Eunice X. Tan, Ning Qi Pang, Beom Kyung Kim, Nicholas Syn, Alfred Kow, Brian K. P. Goh, Daniel Q. Huang
LR was associated with poorer OS (HR 1.44, CI: 1.14-1.81, p<0.01) and DFS (HR 2.71, CI: 2.23-3.28, p<0.01) compared to LT. In uninodular HCC, OS was comparable between LR and LT (p=0.13), but DFS remained poorer (p<0.01). Cohorts that underwent enhanced surveillance had comparable OS between LR and LT (p=0.33).

Editorial

Rules: abide or abandon?
Jie Zhou
Extracellular vesicles small RNA clusters: hit the nail on the head of liver cancer detection
Artur Słomka, Bingduo Wang, Tudor Mocan, Maria González-Carmona, Christian P. Strassburg, Veronika Lukacs-Kornek, Miroslaw T. Kornek
Proton beam therapy to bridge or downstage locally advanced hepatocellular carcinoma to living donor liver transplantation
Chao-Long Chen, Aldwin D. Ong, Jen-Yu Cheng, Chee-Chien Yong, Chih-Che Lin, Chih-Yi Chen, Yu-Fan Cheng
Editorial comment on: “Systemic treatment of hepatocellular carcinoma: an EASL position paper
Daniel H. Ahn, Tanios Bekaii-Saab
Finding a role for cancer vaccines in pancreatic cancer: a model of resilience
Gentry King, Steven Green, E. Gabriela Chiorean
Hepatocellular carcinoma with complete response to the immunotherapy: the oncologist’s dilemma
Mansour Al-Moundhri, Antonio Cubisino, Fabrizio Panaro
The role of postoperative radiotherapy in hepatocellular carcinoma
Joongyo Lee, Jinsil Seong
Single cell analysis informing therapy response in hepatocellular carcinoma and intrahepatic cholangiocarcinoma
Daniel Wai-Hung Ho, Irene Oi-Lin Ng
Hepatitis C treatment in patients with substance use disorder: the faster the better
Antonio Saviano, Lucile Heroin, Pierre Mayer, Thomas F. Baumert
No touch radiofrequency ablation for hepatocellular carcinoma: a conceptual approach rather than an iron law
Olivier Seror
Comment on: development and external validation of a model to predict overall survival in patients with resected gallbladder cancer
Sakti Chakrabarti, Amit Mahipal
Two is better than one: combinatorial receptor targeting enhances hepatocellular carcinoma (HCC) therapeutic response
Celia Sequera, Flavio Maina
Long-term outcomes in patients with non-alcoholic fatty liver disease: further evidence that a multidisciplinary and patient-centred approach to treatment is needed
Giovanni Targher
Editorial comment on: development and external validation of a model to predict overall survival in patients with resected gallbladder cancer
Mairéad G. McNamara
Establishing a blueprint for successful liver transplantation for alcohol-related cirrhosis: the importance of a multidisciplinary team
José Ursic-Bedoya, Hélène Donnadieu-Rigole
Optimizing strategies to reduce alcohol consumption and relapses, improving abstinence in liver transplant recipients
Isabel Legaz, Manuel Muro
Glucose-lowering agents and reduced risk of incident non-alcoholic fatty liver disease: new insights
Alessandro Mantovani, Rosa Lombardi, Andrea Dalbeni