Original Article
Highly variable biodistribution of 68Ga labeled somatostatin analogues 68Ga-DOTA-NOC and 68Ga-DOTA-TATE in neuroendocrine tumors: clinical implications for somatostatin receptor directed PET/CT
This study investigates 68Ga-DOTA-PET imaging for monitoring disease state in NETs and demonstrates significant variability in SUV in both normal tissues as well as in primary and metastatic lesions. The data support the need for incorporation of more reliable quantitative measures for clinical decision making.
One- versus two-stage partial hepatectomy for large resectable solitary hepatocellular carcinomas determined preoperatively to have a narrow resection margin: a propensity score matching analysis
For patients with a large but resectable solitary HCC of >5cm in diameter and a preoperative estimated resection margin, of <1.0cm, two-stage resection could extend resection margins and resulted in significantly better long-term survival outcomes after partial hepatectomy.
Automated liver tumor detection in abdominal ultrasonography with a modified faster region-based convolutional neural networks (Faster R-CNN) architecture
We constructed the model based on Faster region-based Convolutional Neural Networks for the detection of tumor tissues and blood vessels from the sequential liver ultrasound images. The comparison between the proposed model and the based model shows that we achieved better accuracy in tumor detection.
The influence of 18F-fluorodeoxyglucose positron emission tomography/computed tomography on the N- and M-staging and subsequent clinical management of intrahepatic cholangiocarcinoma
PET/CT is superior to conventional imaging in diagnosing lymph node metastasis and distant metastasis, which improves the accuracy of tumor staging from 60.1% to 71.8%, and refines clinical management in 5.8% of ICC patients. PET/CT may bring survival benefits for ICC patients.
Review Article
Comparative effectiveness of medical treatment vs. metabolic surgery for histologically proven non-alcoholic steatohepatitis and fibrosis: a matched network meta-analysis
Using a novel method for network meta-analysis, the effectiveness of surgical and non-surgical therapies including the newly developed drugs was compared. Surgery is more effective to resolve NASH compared to drug treatment and while both are equally effective regarding improvement of fibrosis.
Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with portal vein tumor thrombus: a systematic review
HCC with Type II and Ⅲ PVTT are the most common in the included patients. 22.8% patients are evaluated as partial response after preoperative radiotherapy. Neoadjuvant radiotherapy followed by hepatectomy prolongs the survival for resectable HCC with PVTT.
French Commentary from the ACHBPT
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