Vol 12, No 2 (April 10, 2023): Hepatobiliary Surgery and Nutrition

Original Article

Predictors and long-term prognosis of early and late recurrence for patients undergoing hepatic resection of hepatocellular carcinoma: a large-scale multicenter study
Wen-Tao Yan, Chao Li, Lan-Qing Yao, Hai-Bo Qiu, Ming-Da Wang, Xin-Fei Xu, Ya-Hao Zhou, Hong Wang, Ting-Hao Chen, Wei-Min Gu, Jian-Hong Zhong, Han Wu, Timothy M. Pawlik, Wan Yee Lau, Feng Shen, Tian Yang
This large-scale multicentric study demonstrated that independent predictors associated with early and late recurrence after curative resection for patients with HCC were generally same, although several did differ. The study also showed patients with early recurrence had worse long-term survival than patients with late recurrence.
Living donor liver transplantation for Barcelona clinic liver cancer (BCLC) intermediate-stage hepatocellular carcinoma
Ming Chao Tsai, Chee-Chien Yong, Chih-Che Lin, Wei-Chen Lee, Chih-Chi Wang, Chao-Hung Hung, I-Hsuan Chen, Yu-Fan Cheng, Chang-Chun Hsiao, Tsung-Hui Hu, Chao-Long Chen
Microvascular invasion of hepatocellular carcinoma predicts microvascular invasion of its recurrence: potential implications for salvage liver transplantation?
Stefan Heinrich, Jens Mittler, Juliane Theurer, Dirk A. Ridder, Jens U. Marquardt, Arndt Weinmann, Uwe Scheuermann, Gerd Otto, Peter R. Galle, Beate K. Straub, Hauke Lang
The absence of microvascular invasion in a recurrent hepatocellular carcinoma can be predicted by the histological features of the initial tumor.
Prognostication algorithm for non-cirrhotic non-B non-C hepatocellular carcinoma—a multicenter study under the aegis of the French Association of Hepato-Biliary Surgery and liver Transplantation
Charlotte Maulat, Stéphanie Truant, Christian Hobeika, Louise Barbier, Astrid Herrero, Alexandre Doussot, Johan Gagnière, Édouard Girard, Hadrien Tranchart, Jean-Marc Regimbeau, David Fuks, François Cauchy, Mathieu Prodeau, Antoine Notte, Cyprien Toubert, Ephrem Salamé, Mehdi El Amrani, Sandrine Andrieu, Fabrice Muscari, Jason Shourick, Bertrand Suc
This prognostication algorithm based on the number (≤ or > 2) and size ( 10cm), which could be used as a treatment decision support concerning the need for perioperative therapy. It highlighted distinctive groups of non-cirrhotic HCC patients with different prognoses.
Robotic versus laparoscopic liver resection for huge (≥10 cm) liver tumors: an international multicenter propensity-score matched cohort study of 799 cases
Tan-To Cheung, Rong Liu, Federica Cipriani, Xiaoying Wang, Mikhail Efanov, David Fuks, Gi-Hong Choi, Nicholas L. Syn, Charing C. N. Chong, Fabrizio Di Benedetto, Ricardo Robles-Campos, Vincenzo Mazzaferro, Fernando Rotellar, Santiago Lopez-Ben, James O. Park, Alejandro Mejia, Iswanto Sucandy, Adrian K. H. Chiow, Marco V. Marino, Mikel Gastaca, Jae Hoon Lee, T. Peter Kingham, Mathieu D’Hondt, Sung Hoon Choi, Robert P. Sutcliffe, Ho-Seong Han, Chung-Ngai Tang, Johann Pratschke, Roberto I. Troisi, Go Wakabayashi, Daniel Cherqui, Felice Giuliante, Davit L. Aghayan, Bjorn Edwin, Olivier Scatton, Atsushi Sugioka, Tran Cong Duy Long, Constantino Fondevila, Mohammad Abu Hilal, Andrea Ruzzenente, Alessandro Ferrero, Paulo Herman, Kuo-Hsin Chen, Luca Aldrighetti, Brian K. P. Goh; International robotic and laparoscopic liver resection study group investigators
In a cohort of 100 robotic and 699 laparoscopic liver resections performed for huge tumors, a 1:3 propensity score matched study comparing between robotic and laparoscopic liver resections were performed. Both robotic and laparoscopic liver resections could be performed safely for huge liver tumours. There was no significant difference between the key perioperative outcomes between both groups.

Review Article

A review of 2022 Chinese clinical guidelines on the management of hepatocellular carcinoma: updates and insights
Di-Yang Xie, Kai Zhu, Zheng-Gang Ren, Jian Zhou, Jia Fan, Qiang Gao
The highlight of this review is summarized as follows: This review briefly presented updated recommendations on the management of hepatocellular carcinoma in the 2022 version of Chinese guidelines. Comparisons with updates in the 2022 Barcelona Clinic Liver Cancer guidelines and Japanese Society of Hepatology consensus statement were made to discuss regional variations.

Editorial Commentary

Time to rebuild the doctor-patient relationship in China
Yuxin Wang, Shunda Du
Clinical practice guidelines for acute-on-chronic liver failure: are we ready for reaching global consensus?
Cornelius Engelmann, Thomas Berg
The Japanese Clinical Practice Guidelines for intrahepatic cholangiocarcinoma: a comparison with Western guidelines
Stefan Buettner, Bas Groot Koerkamp
Lenvatinib applicability in the therapeutic strategy of patients with hepatocellular carcinoma
Philippe Merle
Immunotherapy for the treatment of hepatocellular carcinoma: finally in clinical practice
Ciro Celsa, Lucia Cerrito, Leonardo Stella, Roberta Ciccia, Giuseppe Cabibbo, Francesca Romana Ponziani
The Society for Immunotherapy of Cancer clinical practice guideline on immunotherapy for hepatocellular carcinoma
Masatoshi Kudo
Gut microbiome evolution impacts the clinical outcomes of diseases
Lejia Sun, Jiawei Li, Yifei Feng, Yueming Sun
Robotic hepatectomy: challenge and progression
Ligan Zhang, Aoxiao He, Jun Lei, Wenjun Liao
The role of innate immune cells in post-hepatectomy liver regeneration
Yong-Fa Huang, Zhi-Jun Zhu

Editorial

Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)—a fine balance
Kai Tai Derek Yeung, Mikael H. Sodergren
Associating liver partition and portal vein ligation or combined transarterial chemo-embolisation and portal vein embolisation for staged hepatectomy for HBV-related hepatocellular carcinoma
Paschalis Gavriilidis, Timothy M. Pawlik, Tomer Meirson, Daniel Azoulay
Predicting early graft loss in pancreas transplantation using novel imaging techniques: are we there yet?
Samrat Ray, Trevor W. Reichman
Pancreaticoduodenectomy: how to handle a replaced right hepatic artery
Junichi Kaneko, Akihiko Ichida, Yoshikuni Kawaguchi, Kiyoshi Hasegawa
ALPPS versus portal vein embolization for hepatitis B virus-associated hepatocellular carcinoma: a delicate balance between volume and morbidity
Víctor Lopez-Lopez, Kohei Miura, Asuncion Lopez-Conesa, Roberto Brusadin, Alvaro Navarro, Ricardo Robles-Campos
A novel comprehensive ALPPS preoperative risk assessment (CAPRA) score is beneficial in creating a treatment strategy for advanced liver malignancy
Kensuke Yamamura, Toru Beppu, Tatsunori Miyata, Hirohisa Okabe, Katsunori Imai, Takatoshi Ishiko

Images in Clinical Medicine

A 7-year-old girl with giant congenital biliary dilatation
Xiaolei Xu, Cancan Gao, Lizhen Zhu, Xiaobin Feng, Haining Fan