Vol 8, Supplement 1 (March 05, 2019): Hepatobiliary Surgery and Nutrition (3rd Asia-Pacific Cholangiocarcinoma Conference)

Anyaporn Sawasdichai Chailert, Jomnarong Lertsuwan, Nathapol Tasnawijitwong, Tawit Suriyo, Nuchanart Rukadilok, Nuntanit Pholphana, Kevin Gaston, Padma-Sheela Jayaraman, Jutamaad Satayavivad

PDF Pages: AB033 ABSTRACT (944) Open Access

Poster Abstracts

AB034. P-02. Depletion of SRSF1 inhibits proliferation, promotes apoptosis and changes cellular proteome of cholangiocarcinoma cells

Pawee Tangwiriyarotkul, Phichamon Phetchahwang, Sucheewin Krobthong, Sittiruk Roytrakul, Sopit Wongkham, Worasak Kaewkong

PDF Pages: AB034 ABSTRACT (841) Open Access

AB035. P-03. Explore the mutational landscape and immune profile of EBV-associated lymphoepithelioma-like cholangiocarcinoma

Nai-Jung Chiang, Ming-Huang Chen, Ming-Han Tsai, Hung-Wen Tsai, Li-Tzong Chen, Yan-Shen Shan

PDF Pages: AB035 ABSTRACT (963) Open Access

AB036. P-04. The upregulation of Oct4 in acidic extracellular pH is associated with gemcitabine resistance in cholangiocarcinoma cell lines

Phatchareeporn Choodetwattana, Siriporn Proungvitaya, Patcharee Jearanaikoon, Temduang Limpaiboon

PDF Pages: AB036 ABSTRACT (686) Open Access

AB037. P-05. Evaluation of infrared spectral signature associated with pathology as biomarker for cancer progression in cholangiocarcinoma

Patcharaporn Tippayawat, Molin Wongwattanakul, Parichart Boueroy, Chariya Hahnvajanawong, Tidarat Boonmars, Bayden Wood, Philip Heraud, Patcharee Jearanaikoon

PDF Pages: AB037 ABSTRACT (724) Open Access

AB038. P-06. Tumor-infiltrating CD8+ lymphocytes of as a prognostic factor of intrahepatic cholangiocarcinoma

Thanawoot Yothagaree, Prakasit Sa-Ngiamwibool, Supinda Koonmee, Chawalit Pairojkul

PDF Pages: AB038 ABSTRACT (727) Open Access

AB039. P-07. Elevated expression of the key components of polycomb repressive complex 2 is associated with poorer survival outcome in cholangiocarcinoma

Wiphawan Wasenang, Anucha Puapairoj, Chatri Settasatian, Siriporn Proungvitaya, Temduang Limpaiboon

PDF Pages: AB039 ABSTRACT (964) Open Access

AB040. P-08. FOENIX-CCA2: a phase 2 study of TAS-120 in patients with intrahepatic cholangiocarcinoma harboring FGFR2 gene rearrangements

Junji Furuse, Lipika Goyal, Rastsilav Bahleda, Juan Valle, Markus Moehler, Do-Youn Oh, Heung-Moon Chang, Robin Kate Kelley, Milind Javle, Mitesh Borad, Li-Tzong Chen, Nataliya Uboha, Heinz-Josef Klümpen, Peter J. O’Dwyer, Daneng Li, Chigusa Morizane, Jerry Huang, John A. Bridgewater

PDF Pages: AB040 ABSTRACT (1314) Open Access

AB041. P-09. Neoadjuvant chemotherapy with portal vein embolization for initially unresectable hilar cholangiocarcinoma—a case report

Chun-Yi Tsai, Tsung-Han Wu, Chien-Ming Chen, Tze-Chin Chen, Ta-Sen Yeh

PDF Pages: AB041 ABSTRACT (825) Open Access

AB042. P-10. Initial surgical experience for hilar bile duct cancer by incorporating major extended hemihepatectomy including extrahepatic bile duct resection without the aid of portal vein embolization

Chiah-Yang Chai

PDF Pages: AB042 ABSTRACT (843) Open Access

AB043. P-11. Autoantibody screening in sera of patients with cholangiocarcinoma by serological proteomic approach

Mohammad Zahid Mustafa, Zunera Tanveer, Eric Ballot

PDF Pages: AB043 ABSTRACT (729) Open Access

AB044. P-12. Phase 1 study of hepatic arterial infusion (HAI) therapy with floxuridine (FUDR) combined with systemic gemcitabine and oxaliplatin in patients with locally advanced intrahepatic cholangiocarcinoma (ICC)

Patrick Grierson, Aabha Oza, Maria Doyle, Ryan Fields, William Hawkins, Chet Hammill, Andrea Wang-Gillam, Manik Amin, Katrina Pedersen, Kian-Huat Lim, Ashley Morton, Christine Cordova, Kathryn Fowler, Benjamin Tan, William Chapman

PDF Pages: AB044 ABSTRACT (820) Open Access

AB045. P-13. Genomic heterogeneity between Asian and Western intrahepatic cholangiocarcinoma

Reham Abdel-Wahab, Siqin Liu, Jingyu Cao, Jing Hu, Funda Meric-Bernstam, Junjie Xu, Qiang Li, Maolin Yan, Yujie Feng, Jianzhen Lin, Songhui Zhao, Jian Wang, Kai Wang, Mitesh J. Borad, Milind Javle, Haitao Zhao

PDF Pages: AB045 ABSTRACT (931) Open Access

AB046. P-14. TREETOPP: a phase 2/3 study of varlitinib plus capecitabine versus placebo plus capecitabine as second-line treatment in patients with advanced or metastatic biliary tract cancers (BTCs)

Milind M. Javle, Do-Youn Oh, Masafumi Ikeda, Shukui Qin, Wei-Peng Yong, Yee Chao, Nicola McIntyre, Chih-Yi Hsieh, Lilian Chow, Alyssa Chang, Mark McHale, Bertil Lindmark

PDF Pages: AB046 ABSTRACT (881) Open Access

AB047. P-15. Using an integrated microfluidic platform to explore circulating tumor cells in cholangiocarcinoma

Nai-Jung Chiang, Priya Gopinathan, Shang-Cheng Hung, Gwo-Bin Lee, Yan-Shen Shan

PDF Pages: AB047 ABSTRACT (719) Open Access

AB048. P-16. Molecular profiling of intrahepatic cholangiocarcinoma in Taiwan using targeted next-generation sequencing

Nai-Jung Chiang, Chien-Tsung Liu, Kun-Huei Yeh, Jen-Shi Chen, Ming-Huang Chen, Li-Tzong Chen

PDF Pages: AB048 ABSTRACT (1097) Open Access

AB049. P-17. A phase II study of HDAC inhibition to sensitize to immunotherapy in advanced cholangiocarcinoma

Marina Baretti, Rosalind Walker, Jennifer Durham, Brian Christmas, Leslie Cope, Elizabeth M. Jaffee, Nilofer S. Azad

PDF Pages: AB049 ABSTRACT (1008) Open Access

AB050. P-18. Rare adenocarcinoma arising from mucinous cystic neoplasm of liver: case report and literature review

Chia-Chun Hung, Hsiang-Lin Lee

PDF Pages: AB050 ABSTRACT (758) Open Access

AB051. P-19. A phase II study of infigratinib (BGJ398) in previously-treated advanced cholangiocarcinoma containing FGFR2 fusions

Milind Javle, R. Kate Kelley, Sameek Roychowdhury, Karl Heinz Weiss, Ghassan K. Abou-Alfa, Teresa Macarulla, Saeed Sadeghi, Dirk Waldschmidt, Andrew X. Zhu, Lipika Goyal, Mitesh Borad, Wei Peng Yong, Ivan Borbath, Anthony El-Khoueiry, Philip Philip, Susan Moran, Yining Ye, Mary Ising, Nancy Lewis, Tanios Bekaii-Saab

PDF Pages: AB051 ABSTRACT (1244) Open Access

AB052. P-20. Phase 2, open-label study of second-line M7824 treatment in patients with locally advanced or metastatic biliary tract cancer

Mitesh Borad, Milind Javle, Junji Furuse, Chih-Hung Hsu, Markus Moehler, Do-Youn Oh, Joon Oh Park, Lin Shen, Juan Valle, Meng Li, Christoph Helwig, John Bridgewater

PDF Pages: AB052 ABSTRACT (1022) Open Access

AB053. P-21. M7824 (MSB0011359C), a bifunctional fusion protein targeting transforming growth factor β (TGF-β) and PD-L1, in Asian patients with pretreated biliary tract cancer (BTC): efficacy by BTC subtype

Changhoon Yoo, Do-Youn Oh, Hye Jin Choi, Masatoshi Kudo, Makoto Ueno, Shunsuke Kondo, Li-Tzong Chen, Motonobu Osada, Christoph Helwig, Isabelle Dussault, Masafumi Ikeda

PDF Pages: AB053 ABSTRACT (1707) Open Access

AB054. P-22. An international collaborative of Clinical Nursing Practice Guidelines for care of patients with cholangiocarcinoma

Lorraine Drapek, Susan Acquisto, Renuka Iyer

PDF Pages: AB054 ABSTRACT (840) Open Access

AB055. P-23. The impact of perioperative CA19-9 change on the survival and recurrence patterns after adjuvant chemoradiotherapy in extrahepatic cholangiocarcinoma

Byoung Hyuck Kim, Eunji Kim, Kyubo Kim, Jin-Young Jang, Sun Whe Kim, Do-Youn Oh, Eui Kyu Chie

PDF Pages: AB055 ABSTRACT (745) Open Access

AB056. P-24. Characterization of cholangiocarcinoma cells by Fourier transform infrared spectral pattern

Molin Wongwattanakul, Sirinart Chio-Srichan, Chanvit Leelayuwat, Temduang Limpaiboon, Philip Heraud, Patcharee Jearanaikoon

PDF Pages: AB056 ABSTRACT (952) Open Access

AB057. P-25. Clinicopathologic features of intraductal tubulopapillary neoplasms of the bile duct

Janelle Rekman, Russell Dorer, Morgan Bonds, George Baison, Flavio Rocha

PDF Pages: AB057 ABSTRACT (716) Open Access

AB058. P-26. Utility of cholangioscopy-targeted biopsy for diagnosis of biliary neoplasms: experiences from referral hospitals in Eastern and Western countries

Phonthep Angsuwatcharakon, Osman Ahmed, Jeerawat Maytapa, William Ross, Brian Weston, Wiriyaporn Ridtitid, Pradermchai Kongkam, Rungsun Rerknimitr, Jeffrey H. Lee

PDF Pages: AB058 ABSTRACT (749) Open Access

AB059. P-28. Is cholangiocarcinoma the only concern in western adult patients with choledochal cyst (CC) disease and anomalous pancreaticobiliary junction (APBJ)?

George N. Baison, Morgan M. Bonds, Janelle F. Rekman, Flavio G. Rocha, Scott W. Helton, Richard A. Kozarek

PDF Pages: AB059 ABSTRACT (801) Open Access

AB060. P-31. Complete response to immunotherapy in cholangiocarcinoma with peritoneal metastases and high PD-L1 expression: a case report

Yung-Yeh Su, Nai-Jung Chiang, Yih-Jyh Lin, Yan-Shen Shan, Li-Tzong Chen

PDF Pages: AB060 ABSTRACT (1204) Open Access

AB061. P-32. Multicenter, randomized phase II trial of S-1, leucovorin, oxaliplatin and gemcitabine (SLOG) in chemo-naïve advanced biliary tract cancer: a Taiwan Cooperative Oncology Group study

Jen-Shi Chen, Li-Yuan Bai, Ming-Huang Chen, Nai-Jung Chiang, Chiun Hsu, Shih-Hung Yang, Yung-Yeh Su, Yan-Shen Shan, Li-Tzong Chen

PDF Pages: AB061 ABSTRACT (983) Open Access

AB062. P-33. Efficacy and safety of varlitinib, a reversible pan-HER tyrosine kinase inhibitor, in combination with platinum-based regimens in biliary tract cancers: a pooled analysis from three phase 1 studies

Aaron C. Tan, Aaron C. Tan, Do-Youn Oh, Yee Chao, Chih-Yi Hsieh, Wei-Ling Chang, Fenny Isanto, Ying-Chen Chen, Mark McHale, Bertil Lindmark, Matthew C. H. Ng

PDF Pages: AB062 ABSTRACT (909) Open Access

AB063. P-34. A multicenter, phase 1b/2 study of varlitinib plus gemcitabine and cisplatin (gem/cis) for treatment naïve advanced or metastatic biliary tract cancer (BTC)

Do-Youn Oh, Wei-Peng Yong, Li-Tzong Chen, Ji-Won Kim, Alex Yuang-Chi Chang, Jin Hyun Park, Chih-Yi Hsieh, Hsuan-Jen Shih, Nicola McIntyre, Ying-Chen Chen, Wei-Ling Chang, Mark McHale, Bertil Lindmark

PDF Pages: AB063 ABSTRACT (809) Open Access

AB064. P-35. Quantitative magnetic resonance cholangiopancreatography applications in primary sclerosing cholangitis and cholangiocarcinoma

Stephanie Seah, Ged Ridgway, Gary Woodward, Marija Mavar, Carlos Ferreira, Andrea Borghetto, John Connell, Matt Kelly, Michael Brady, Rajarshi Banerjee

PDF Pages: AB064 ABSTRACT (1058) Open Access

AB065. P-36. Debio 1347 in patients with cholangiocarcinoma harboring an FGFR gene alteration: preliminary results

Matthew C. H. Ng, Lipika Goyal, Yung-Jue Bang, Do-Youn Oh, Tsu-Yi Chao, James M. Cleary, Martin Henner Voss, Funda Meric-Bernstam, Gopa Iyer, Rebecca Suk Heist, Nobuya Ishii, Yulia Kirpicheva, Anna Pokorska-Bocci, Anne Vaslin, Youyou Hu, Claudio Zanna, David Hyman, Keith Flaherty

PDF Pages: AB065 ABSTRACT (1380) Open Access

AB066. P-37. Epidemiology study of extrahepatic cholangiocarcinoma in Korea

Dong Uk Kim, Tae Hoon Lee, Sang Hyub Lee, Young Koog Cheon

PDF Pages: AB066 ABSTRACT (1026) Open Access

AB067. P-38. Microbial analysis of gallstones and gallbladder tissue by MALDI-TOF in patients with symptomatic gallstones

Dimple Kalsi, Usha Dutta, Priyanka Popli, Pallab Ray, Lileswar Kaman, Divya Dahiya, Arunanshu Behera, Pankaj Sharma, Harshal Mandavdhare, Vishal Sharma

PDF Pages: AB067 ABSTRACT (995) Open Access

AB068. P-39. Comparison of selective internal radiation therapy (SIRT) versus sorafenib in patients with locally advanced hepatocellular carcinoma in Mongolia: a subgroup analysis of SIRveNIB study

Ariunaa Khasbazar

PDF Pages: AB068 ABSTRACT (1064) Open Access

Disclosure:

The supplement “3rd Asia-Pacific Cholangiocarcinoma Conference”was commissioned by the editorial office, Hepatobiliary Surgery and Nutrition without any sponsorship or funding. Flavio Rocha and Li-Tzong Chen served as the unpaid Guest Editors for the supplement.