Vol 11, No 4 (August 04, 2022): Hepatobiliary Surgery and Nutrition

Original Article

Transcatheter arterial embolization-salvaged ALPPS, a novel ALPPS procedure especially for patients with hepatocellular carcinoma and severe fibrosis/cirrhosis
Yuanfei Peng, Zheng Wang, Xudong Qu, Feiyu Chen, Huichuan Sun, Xiaoying Wang, Zhenbing Ding, Min Tang, Lei Yu, Xinrong Yang, Qiang Gao, Zhaoyou Tang, Wan Yee Lau, Jia Fan, Jian Zhou
The ALPPS for HCC with fibrosis/cirrhosis is often associated with limited growth of future liver remnant (FLR). The new TAE-Salvaged ALPPS can induce significant FLR increase in patients with HCC and fibrosis/cirrhosis who fail to achieve sufficient FLR hypertrophy after conventional ALPPS stage-1.
The role of intraoperative electron radiotherapy in centrally located hepatocellular carcinomas treated with narrow-margin (<1 cm) hepatectomy: a prospective, phase 2 study
Liming Wang, Yunhe Liu, Weiqi Rong, Fan Wu, Weibo Yu, Kan Liu, Shengtao Lin, Yiling Zheng, Kai Zhang, Tana Siqin, Changcheng Tao, Mei Liu, Bo Chen, Qinfu Feng, Jianxiong Wu
Intraoperative Electron Radiotherapy (IOERT) significantly improved the recurrence free survival rates in patients with centrally located hepatocellular carcinoma who underwent narrow-margin (<1cm) hepatectomy. Furthermore, MVI (+) patients receiving IOERT had improved recurrence free and overall survival outcomes compared to MVI (-) patients.
Functional assessment of liver regeneration after major hepatectomy
Fadi Rassam, Pim B. Olthof, Bart Takkenberg, Marc G. Besselink, Olivier R. Busch, Joris I. Erdmann, Rutger-Jan Swijnenburg, Krijn P. van Lienden, Ulrich H. Beuers, Roelof J. Bennink, Thomas M. van Gulik
The aim of this study was to evaluate the early postoperative changes in remnant liver function, volume and elasticity after major liver resection and its correlation with postoperative outcomes. This information can provide new insights that influence selection of candidates for liver resection, their postoperative monitoring and their management.
Prospective evaluation of 18F-FDG positron emission tomography in the preoperative staging of patients with hepatic colorectal metastases
Tim Akhurst, Mithat Gönen, Raymond E. Baser, Lawrence H. Schwartz, Scott Tuorto, Lynn A. Brody, Anne Covey, Karen T. Brown, Steven M. Larson, Yuman Fong
A prospective, blinded study comparing utility of 18F-FDG-PET to CT and CT portography as was conducted as staging prior to resection of hepatic colorectal metastases. FDG-PET was found to be an important test, affecting treatment decisions in nearly one-third of patients.

Review Article

Cholangiocarcinoma: a review of the literature and future directions in therapy
Ritika Halder, Akshay Amaraneni, Rachna T. Shroff
Cholangiocarcinoma remains one of the challenges among aggressive adenocarcinoma subtypes in the United States. Early detection remains a significant challenge and surgical resection and transplant are available to very few patients. Improvements in palliative treatments have come in the form of new chemotherapeutic regimens as well as targeted therapies.
Alternatives to left lateral sector in paediatric liver transplantation—a systematic review on monosegmental and reduced grafts
Paschalis Gavriilidis, Ernest Hidalgo
Monosegmental, reduced and hyper-reduced liver transplantation offer excellent results to treat neonates and small infants.

Editorial

Neoadjuvant therapy for resectable pancreatic cancers
Yosuke Inoue, Hiromichi Ito, Yu Takahashi
Multi-disciplinary clinic models for the management of non-alcoholic fatty liver disease
Mirko Zoncapè, Antonio Liguori, Emmanuel A. Tsochatzis
Durvalumab plus tremelimumab in unresectable hepatocellular carcinoma
Masatoshi Kudo
The management strategy of pancreatic cancer in the era of systemic therapy—“Surgery First” or “Surgery Last”?
Yinmo Yang, Xiaodong Tian
Eat more natural dietary fiber and whole grains to minimize liver disease risk
Rachel M. Golonka, Beng San Yeoh, Matam Vijay-Kumar
Importance of an appropriate number of examined lymph nodes in patients with pancreatic cancer—the more the better?
Toshiro Ogura, Hiroyuki Ishida, Amane Takahashi, Yoshiyuki Kawashima
Placement of vein grafting in liver surgery at the time of the R1 vascular concept and the communicating veins
Guido Torzilli
Construction of an intrahepatic portosystemic shunt using the magnetic compression technique: preliminary experiments in a canine model
Miaomiao Zhang, Jia Ma, Yingfeng An, Yi Lyu, Xiaopeng Yan
Perihilar-cholangiocarcinoma: what really matters?
Fabrizio Di Benedetto, Paolo Magistri, Stefano Di Sandro
It’s time to propose a uniform criteria for determining “clinical complete response” in hepatocellular carcinoma
Lei Zhao, Haitao Zhao, Huichuan Sun
To resect or not to resect?—the dilemma in oligometastatic breast cancer
Sara Lonardi, Valentina Guarneri
Difficulties and opportunities of hospice care—the role of doctors
Yali Cong