Vol 12, No 6 (December 01, 2023): Hepatobiliary Surgery and Nutrition

Original Article

Laparoscopic anatomical versus non-anatomical liver resection for hepatocellular carcinoma in the posterosuperior segments: a propensity score matched analysis
Boram Lee, Jai Young Cho, Ho-Seong Han, Yoo-Seok Yoon, Hae Won Lee, Jun Suh Lee, Moonhwan Kim, Yeongsoo Jo
LNAR is feasible option for patients with HCC located in PS segments, and can provide acceptable oncologic outcomes that are comparable to those of LAR. LNAR can be considered for patient with tumor located in PS segment when LAR is not feasible.
Influence of immunosuppressive drugs on natural killer cells in therapeutic drug exposure in liver transplantation
Rongrong Qin, Jiwei Qin, Xuefeng Li, Zhijun Xu, Peiqi He, Xiaodong Yuan, Cheng Sun, Björn Nashan
The study demonstrates that the cytolytic activity of NK cells in a mTORI including immunosuppression regimen is better preserved than with MMF and might support one potential explanation for a reduced recurrence rate of HCC after liver transplantation.
A novel nomogram for prognosis stratification in salvage liver transplantation: a national-wide study with propensity score matching analysis in China
Kai Wang, Fengqiang Gao, Siyi Dong, Jialu Ding, Libin Dong, Chuxiao Shao, Zhoucheng Wang, Xun Qiu, Xuyong Wei, Zhengxin Wang, Jiayin Yang, Qiang Xia, Shusen Zheng, Xiao Xu
This study based on a huge data set from mainland China compared post-transplant survival of patients fulfilling Milan or Hangzhou criteria between SLT and PLT groups with propensity score matching analysis. Furthermore, we developed risk stratification system based on the nomogram to classify SLT recipients.
A novel clinical model for risk prediction and stratification of new-onset diabetes mellitus after distal pancreatectomy
Zhihong Chen, Ning Shi, Cheng Xing, Yiping Zou, Yuanpeng Zhang, Zhenrong Chen, Fan Wu, Haosheng Jin, Rufu Chen, Menghua Dai
The incidence of new-onset diabetes after distal pancreatectomy remains high, particularly in patients with benign or low-grade malignant pancreatic lesions. The novel nomogram has satisfactory accuracy, reliability and utility in predicting post-pancreatectomy diabetes and may facilitate clinical decision-making by enhancing intervention and reducing unnecessary costs.
Efficacy and safety of subsequent radiotherapy in patients with advanced-stage hepatocellular carcinoma treated with immune checkpoint inhibitors
Cong Ning, Jun Jia, Xinmu Zhang, Jing Sun, Yunchao Wang, Jingnan Xue, Longhao Zhang, Xiaorong Hou, Xiaobo Yang, Xinting Sang, Xuezhang Duan, Haitao Zhao
Subsequent external radiotherapy could be used as a salvage treatment strategy for patients with advanced-stage hepatocellular carcinoma who have lesion enlargement or new lesions during immune checkpoint inhibitor therapy, and it shows reliable efficacy and acceptable safety.
Peri-operative extracorporeal membrane oxygenation in adult and pediatric living donor liver transplantation: a single-center experience
Itsuko Chih-Yi Chen, Leona Bettina P. Dungca, Chee-Chien Yong, Wei Ho, Jiunn-Jye Sheu, Chao-Long Chen

Editorial Commentary

Primary hospitals in China: current state, challenges, and solutions
Ziyi Wang, Ge Zhang
Can liver stiffness measurement accurately predict disease progression and clinical outcome in patients with metabolic dysfunction-associated steatotic liver disease and bridging fibrosis or cirrhosis?
Diederick J. van Doorn, Adriaan G. Holleboom, R. Bart Takkenberg, Joanne Verheij, Marten A. Lantinga
Clinical utility of non-invasive tests to predict clinical outcomes in non-alcoholic fatty liver disease
Shi Yan Lee, Darren J. H. Tan, Wen Hui Lim, Cheng Han Ng, Mark Muthiah, Daniel Q. Huang
Is tenofovir disoproxil fumarate superior to entecavir for prevention of hepatocellular carcinoma in patients with chronic hepatitis B?
Lisa M. van Velsen, Milan J. Sonneveld, Karel J. van Erpecum
Futibatinib: new targeted therapy in intrahepatic cholangiocarcinoma
Rita Khoury, Nadine Khalife, Rebecca Ibrahim, Khalil Saleh
Surveillance for hepatocellular carcinoma in non-alcoholic fatty liver disease patients: towards personalized risk stratification
Kunhee Kim, Jun Yong Park
Hepatocellular carcinoma extracellular vesicle ECG score as a diagnostic tool close to the ideal
Artur Słomka, Tudor Mocan, Arnulf G. Willms, Veronika Lukacs-Kornek, Miroslaw T. Kornek
New insights in the metabolic function related to gut microbiota in the process of liver regeneration
Nan Jiang, Zhen Wang, Kefei Yuan
The power of prevention: how tenofovir and entecavir are changing the game in hepatocellular carcinoma
Endrit Shahini, Rossella Donghia, Antonio Facciorusso
An ever-increasing metabolic dysfunction-associated fatty liver disease-related hepatocellular carcinoma: what are problems and countermeasures?
Shigeo Shimose, Tsubasa Tsutsumi, Dan Nakano, Tomoya Sano, Keisuke Amano, Takumi Kawaguchi
Metabolic dysfunction-associated fatty liver disease and hepatocellular carcinoma: present and future
Feng Gao, Gang Chen, Christopher D. Byrne, Giovanni Targher, Tan To Cheung, Ming-Hua Zheng
Fatty liver disease and risk of all cause and cause-specific mortality outcomes in the older population
Josh Bilson, Christopher D. Byrne
Modern surgical approach to hepatocellular carcinoma
Paolo Magistri, Gian Piero Guerrini, Stefano Di Sandro, Fabrizio Di Benedetto
Up-to-date global epidemiology of nonalcoholic fatty liver disease
Richie Manikat, Aijaz Ahmed, Donghee Kim
Managing portal hypertension in patients with liver cirrhosis and hepatocellular carcinoma: non-invasive diagnosis and systemic treatment considerations
Woo Kyoung Jeong
The vascular endothelial growth factor system—a new player in the pathogenesis and development of metabolic dysfunction-associated steatotic liver disease
Henning Grønbæk, Anders Mellemkjær, Søren Nielsen, Faidon Magkos
Proton beam therapy for downstaging hepatocellular carcinoma with lobar portal vein tumor thrombosis to living donor liver transplantation
Chao-Long Chen, Leona Bettina P. Dungca, Chee-Chien Yong, Itsuko Chih-Yi Chen, Yu-Fan Cheng, Jen-Yu Cheng, Yen-Yang Chen