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Original Article
Predictive model for very early recurrence of patients with perihilar cholangiocarcinoma: a machine learning approach
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Pages: 3-15
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The machine learning-based online calculator predicts very early recurrence after curative-intent surgery for perihilar cholangiocarcinoma. This tool aids in identifying patients most likely to benefit from resection and informs them of the anticipated early post-operative recurrence risk.
The gut-liver axis links the associations between serum carotenoids and non-alcoholic fatty liver in a 7.8-year prospective study
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Pages: 16-32
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The biomarkers of the gut-liver axis, including the Ruminococcaceae and Veillonellaceae families, along with fecal and serum metabolites like medium-chain fatty acids, bile acids, carnitines, organic acids, and amino acids, provide mechanistic linkage the beneficial association of serum carotenoids and incidence/presence NAFLD.
Effects of exercise and nutrition in improving sarcopenia in liver cirrhosis patients: a systematic review and meta-analysis
A combination of exercise and nutrition interventions significantly improved sarcopenia in patients with liver cirrhosis for 12 months. Skeletal muscle index and albumin levels are positively correlated with these strategies. Prevention of sarcopenia in these patients requires a healthy diet and regular exercise.
Plasma GLP-1 and metabolic dynamics during human liver regeneration and their association with posthepatectomy liver failure
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Pages: 49-65
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Lipid metabolism is altered after liver resection, especially in patients developing posthepatectomy liver failure (PHLF). GLP-1 and GLP-2 regulate lipid metabolism, with perioperative levels significantly affected. Preoperative GLP-1 is strongly linked to PHLF, potentially enhancing prediction models and highlighting the metabolic aspect of liver regeneration.
Review Article
2024 latest report on hepatitis B virus epidemiology in China: current status, changing trajectory, and challenges
China has significantly reduced HBV prevalence through measures such as universal vaccination, lowering the HBsAg positivity rate to 5.86% and achieving a 99.6% vaccination coverage rate. However, challenges remain in improving diagnosis, enhancing treatment access, and addressing disparities to meet WHO's 2030 elimination goals.
Editorial
French Editorial Commentary from the ACHBPT
Editorial Commentary
Letter to the Editor
