Editorial Commentary
Original Article
A combined pre- and intra-operative nomogram in evaluation of degrees of liver cirrhosis predicts post-hepatectomy liver failure: a multicenter prospective study
The multicenter prospective study demonstrated that either preoperative CSS or intra-operative DSM was closely correlated with histopathological stages of cirrhosis. Furthermore, high level of CSS or DSM indicated the risks of PHLF, and the nomograms including these two parameters can effectively predict PHLF.
Clinical and molecular heterogeneity associated with tumor sidedness in colorectal liver metastasis: a multicenter propensity cohort study
The clinicopathological features, underlying molecular profiles, and drivers of left-sided colorectal liver metastasis differ from those of right-sided disease. Standardized, screening, diagnostic, and therapeutic strategies are required to optimize outcomes.
Physical activity decreases in patients on the liver transplant waiting list and influences postoperative outcome—a prospective cohort study
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Pages: 229-240
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Over time, there is a significant decrease of moderate physical activity (MPA) after week 40 on the wait list for liver transplantation (LT). Female patients and patients receiving nutritional support had an increase in MPA. Reduced MPA significantly associated with adverse outcome post-LT.
Evaluation of the economic impact of the robotic approach in major and postero-superior segment liver resections: a multicenter retrospective analysis
Despite higher intraoperative expenses compared to OLS, RLS demonstrated lower overall postoperative costs, supporting its potential cost-effectiveness. The evolving robotic marketplace is expected to reduce RLS costs, further contributing to its favorability. This emphasizes the need for ongoing evaluations of technological advancements and training programs.
Glutamatergic neurons in the paraventricular nucleus of the hypothalamus participate in the regulation of visceral pain induced by pancreatic cancer in mice
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Pages: 258-272
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Targeting glutamatergic neurons in the PVN effectively alleviates visceral pain in pancreatic cancer in mice, thereby presenting a novel target and treatment modality for the clinical management of pancreas-related pain.
Review Article
Molecular profiling and patient selection for the multimodal approaches for patients with resectable colorectal liver metastases
Many clinical variables have guided patient selection and surgical timing for the treatment of resectable colorectal liver metastases, coactively using surgery and systemic treatment. This review explores forthcoming improvements in molecular and genetic profiling as promising tools for patient selection in a more tailored approach.
Insights from Seoul National University Hospital’s experience: a systematic review of pure laparoscopic donor hepatectomy progression
The article highlights the progression of pure laparoscopic donor hepatectomy (PLDH) at Seoul National University Hospital, encompassing full right and left hepatectomies. It emphasizes the safety, feasibility, and expanded selection criteria for donors, leading to a shift from open surgery to pure laparoscopic procedures in donor hepatectomy and even in liver transplantation.
French Editorial Commentary from the ACHBPT
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