Vol 14, No 3 (June 01, 2025): Hepatobiliary Surgery and Nutrition

Our intention-to-treat analysis revealed that ABOi-LDLT improved survival for MELD ≥30 patients, over awaiting DDLT in the severe organ shortage regions. ABOi-LDLT demonstrated comparable posttransplant outcomes to ABOc-LDLT and DDLT with acceptable donor complications. ABOi-LDLT is a feasible treatment option in high MELD patients.

The objective of this study is to identify prognostic factors for GBC post-surgery. Our analysis reveals that factors such as LMR, CA 19-9 level, lymph node status, tumor location, etc., are associated with prognosis, providing valuable insights for clinicians and patients, particularly those facing prognostic challenges.

Preliminary reports on liver resection following transarterial radioembolization (TARE) for hepatocellular carcinoma (HCC) show promising oncological outcomes. Nonetheless, postoperative biliary complications are underreported. Our retrospective study reveals a 20% bile leak rate, with intervals shorter than 6 months between TARE and surgery posing higher risks.

Preoperative chemotherapy in colorectal liver metastases (CRLM) improves resectability and survival but may lead to chemotherapy-associated liver injury (CALI). This study links splenic hypertrophy (SH) post-chemotherapy, to postoperative liver-specific complications (LSC) in CRLM patients undergoing major liver resection, suggesting SH as a predictive marker for LSC.

The proposed ERAS protocol for LTx in this study can provide a safe management tool to monitor the patient and provide quality service with low morbidities and mortality throughout the observation period.

This study is the first to conduct an umbrella review that investigated the effect of surgical-related factors on POPF. A citation matrix was combined with AMSTAR2 to identify and select overlapping Mata-Analyses. The GRADE was used to quantify the strength of the evidence.